Registration Dossier
Registration Dossier
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EC number: 946-154-0 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of the read across study, the test substance is considered to be hydrolytically stable.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 50 °C
Additional information
A study was conducted to determine the hydrolysis potential of the read across substance, mono- and di- C12 PSE, K+, at different pH values according to OECD Guideline 411. According to the guideline, a preliminary test (Tier 1) was performed at 50°C±0.5°C at pH 4, 7, 9 and additionally at pH2. Aliquots of each test solutions were analysed to measure the decrease of monoester and diester derivatives after 120 h incubation at 50°C using the LC/MS analytic.No decreases >10% of mono- and diester has been detected at pH 7 and 9. At pH 4, the results were in the range of uncertainness of the measuring method (approximately 10%); at pH 2 the expected hydrolysis was >10%. The half-life at 25°C was considered to be > 1 year for pH 7 and 9. Therefore, based on the results of the read across study, the test substance is considered to be hydrolytically stable (Hasemann, 2012).
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