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EC number: 290-998-6 | CAS number: 90295-08-2
Non harmful/toxic for fish after short-term exposures
The existing data on Direct Blue 199 sodium salt (i.e. Direct Blue 199_Na) have been taken into account in order to assess the potential for short-term toxicity to fish of Direct Blue 199. The usage of information on Direct Blue 199_Na, which has the same main component and with a different counter ion, can be considered as suitable and appropriated because the difference in salification is expected to not influence the characteristics related to the specific end-point. The impurity profile does not impact on the read across proposed. Details on the approach followed are included in the document attached to the IUCLID section 13.
Direct Blue 199_Na was tested for short-term toxic to fish at different lot concentrations. In some cases the test procedures are scientifically acceptable, while in other many details are missing. In all case there are no evidence that the concentration of the substance being tested has been satisfactorily maintained throughout the tests. The substance is very soluble in water and it does not undergo to readily abiotic degradation, thus it is expected that Direct Blue 199_Na would be bioavailable during the testing period. Despite the Direct Blue 199_Na content in the batches tested was low, it has to be taken into account that the assays were performed at very high concentrations (up to 1000 mg/l).
Despite the reliability cannot be confirmed, in all cases the LC50 recorded was much higher than 100 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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