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EC number: 228-504-8 | CAS number: 6283-92-7
Propanoic acid, 2-hydroxy, C12-C16 (even numbered) alkyl esters (15% solution) was not a sensitizer to guinea pig skin. Ten white male guinea pigs were treated using intracutaneous injections of 0.1% Propanoic acid, 2-hydroxy, C12-C16 (even numbered) alkyl esters (15% active) three times a week for a total of ten injections. The first injection was 0.5 ml and the remaining injections were 0.1 ml. Sterile saline was used as the control and the same amounts as test material were injected. Two weeks following the tenth injection, all animals were challenged with 0.05 ml Propanoic acid, 2-hydroxy, C12-C16 (even numbered) alkyl esters (15% solution) on a virgin site. The test sites were scored 24 hours after each injection. No dermal reactions were exhibited during either the induction phase or challenge phase of the study.
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