1-(5,5-dimethyl-1-cyclohexen-1-yl)pent-4-en-1-one

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental dates: 25 May 2017 to 06 June 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

23 March 2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

as amended by Commission Regulation (EC) 761/2009

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Inspected on 05/07/2016 / Signed on 28/10/2016

Type of method:

gas saturation method

Key result

Temp.:

25 °C

Vapour pressure:

1.34 Pa

Results of the vapor pressure determinations

Saturator Column.	Temperature (°C)	Volume* V (mL)	Mass of test item in Trap 1 (µg)	Mass of test item in Trap 2 (µg)	Total mass of test item (µg)	Vapor pressure (Pa)	Average Vapor pressure [Pa] (Std Dev)
A	15	46484	1870	0	1870	0.502	0.499 (0.005)
B		61675	2440	0	2440	0.493
C		77929	3130	0	3130	0.501
A	25	36674	3740	0	3740	1.31	1.31 (0.004)
B		48299	4900	0	4900	1.31
C		61483	6270	0	6270	1.31
A	35	10356	2710	0	2710	3.48	3.47 (0.03)
B		13741	3550	0	3550	3.44
C		17362	4550	0	4550	3.49

  * corrected volume at test temperature

                                     

The regression parameters of the Vapour Pressure curve ln(VP) = f (1/T) are:

slope = -8613

intercept = 29.18

r²= 0.999

Conclusions:

Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).

Executive summary:

The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, gas saturation method. Determinations were conducted at 15, 25 and 35°C, with three flow rates per temperature. Mass of evaporated test item was quantified by GC. Vapor pressure at 25 °C was interpolated from the regression.

The vapor pressure of the test item has been determined to be 1.34 Pa at 25 °C.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:

1.34 Pa

at the temperature of:

25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. The result is retained as key data for purpose of CSA.