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EC number: 265-747-9 | CAS number: 65405-84-7
In the toxicity test, the test item was assayed at a maximum dose level of 5000 microf/plate and at four does levels spaced at approximately half - log intervals: 1580, 500, 158 and 50 microg/plate. Toxicity as indicated by the thinning of the background lawn and/or reduction in revertant numbers was observed with TA1537 and TA100 both in the absence and presence of S9 metabolic avctivation and with TA102 in its absence. With TA100 tester strain the toxic effects were not dose related but evident at all dose levels.
Dose levels used with all tester strains were selected on the basis of the results obtained in an additional experiment where the dose range assayed proved to be too toxic. Toxicity as indicated by thinning of the background law and reduction in revertant numbers was observed at higher dose levels with all tester strains both in the absence and presence of S9 metabolic activation. No increase in revertant numbers were observed at any concentrations assays.
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