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EC number: 232-178-2 | CAS number: 7789-60-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- Data from NTRL report
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- Short term toxicity test was performed in Daphnia magna for 48 hrs at different concentrations.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Phosphorus tribromide
- Molecular formula : Br3P
- Molecular weight : 270.686 g/mol
- Smiles notation : P(Br)(Br)Br
- InChl : 1S/Br3P/c14(
2)3
- Substance type: Inorganic
- Physical state: Liquid - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Hardness:
- 88 mg/L
- Test temperature:
- 20 ±2 °C
- Nominal and measured concentrations:
- nominal concentration: 0.0, 6.25, 12.5, 25.0, 50.0 or 100.0 mg/L
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 6.25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 22.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The endpoint for the Phosphorus tribromide (7789-60-8) for short term toxicity to aquatic invertebrates was determined to be NOEC and EC50 value at 6.25 mg/l and 22.6 mg/lconcentration
- Executive summary:
Short term toxicity to aquatic invertebrates was performed at different concentrations as0.0, 6.25, 12.5, 25.0, 50.0 or 100.0 mg/L. Experiment performed in static condition in fresh water for 48 hrs. Mortality was observed and effective concentration was found to be 22.6 mg/L (18.2 - 27.9 mg/L confidence limit).
Therefore,the endpoint for the Phosphorus tribromide (7789-60-8) for short term toxicity to aquatic invertebrates was found to be NOEC and EC50 value at 6.25 mg/l and 22.6 mg/l concentration.
Based on the value, the Phosphorus trichloride was considered to be toxic to aquatic invertebrates and can be considered to be classified in aquatic chronic 3 category a per the CLP regulations.
Reference
Description of key information
Short term toxicity to aquatic invertebrates was performed from HSDB,2016 and NTRL report, 1997 for phosphorus tribromide at different concentrations as 0.0, 6.25, 12.5, 25.0, 50.0 or 100.0 mg/L. Experiment performed in static condition in fresh water for 48 hrs. Mortality was observed and effective concentration was determined to be 22.6 mg/L (18.2 - 27.9 mg/L confidence limit). Therefore, the endpoint for the Phosphorus tribromide (7789-60-8) for short term toxicity to aquatic invertebrates was determined to be NOEC and EC50 value at 6.25 mg/l and 22.6 mg/l concentration. Based on the value, the Phosphorus tribromide was considered to be toxic to aquatic invertebrates and can be considered to be classified in aquatic chronic 3 category a per the CLP regulations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 22.6 mg/L
Additional information
Short term toxicity to aquatic invertebrates was summaries with one experimental study , one prediction for Phosphorus tribromide (7789-60-8) and one experimental study with read across.
Short term toxicity to aquatic invertebrates was performed from HSDB,2016 and NTRL report, 1997 for phosphorus tribromide at different concentrations as 0.0, 6.25, 12.5, 25.0, 50.0 or 100.0 mg/L. Experiment performed in static condition in fresh water for 48 hrs. Mortality was observed and effective concentration was determined to be 22.6 mg/L (18.2 - 27.9 mg/L confidence limit). Therefore, the endpoint for the Phosphorus tribromide (7789-60-8) for short term toxicity to aquatic invertebrates was determined to be NOEC and EC50 value at 6.25 mg/l and 22.6 mg/l concentration. Based on the value, the Phosphorus tribromide was considered to be toxic to aquatic invertebrates and can be considered to be classified in aquatic chronic 3 category a per the CLP regulations.
Using the EPI suite, ECOSAR version 1.1, the LC 50 value for short term toxicity to aquatic invertebrates was predicted. On the basis of this program, the LC 50 value for short term toxicity to aquatic invertebrates was predicted to be72.88mg/l for Phosphorus tribromide (7789-60-8) in 48 hrs. Based on the value, the Phosphorus tribromide was considered to be toxic to aquatic invertebrates and can be considered to be classified in aquatic chronic 3 category a per the CLP regulations.
Study on read across Phosphorus trichloride (7719-12-2) from SIDS Assessment Report, 2004 in Daphnia magna for 48 hrs at different six concentrations along with control. The test was performed without feeding to Daphnia magna. 10 neonates were taken for each concentration at 18-20 degree C temperature. pH and oxygen values measured at the end of the test. After the experiment, the EC 50 value for Phosphorus trichloride (7719-12-2) was determined to be 35.4 mg/l.
Based on the above data for the target and functionally related read across chemicals, it can be considered the substance was considered to be toxic to aquatic invertebrates andcan be classified in aquatic chronic 3 as per the CLP regulations.
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