Commiphora myrrha, ext.

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

24 November 2015 to 11 January 2016

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

The study was conducted according to an internationally recognized method, and under GLP. Restriction apply considering that a potential deformation of the pycnometer may occur when the heated test item is placed on the apparatus. Therefore a checking the apparatus volume after the test is recommended to confirm that the result can be expressed with 4 decimals. Test substance is adequately specified. Therefore validation with slight restrictions applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP compliance programme (inspected on 17 June 2015 / signed on 24 September 2015)

Type of method:

pycnometer method

Key result

Type:

density

Density:

1 196 kg/m³

Temp.:

20 °C

Key result

Type:

relative density

Remarks:

D20/4

Density:

1.196 other: unitless

Temp.:

20 °C

Table 4.4/1: Density – results

 

Measurement	Determination
	1	2
Mass of glass vessel (g)	37.6740
Mass of glass vessel and purified water at 21.8 °C (g)	77.9064
Mass of glass vessel and test item at 20.0 °C (g)	85.9252	85.8986
Density of water at 21.8 °C (kg/m^3)	997.82
Density (kg/m^3)	1.197 x 10^3	1.196 x 10^3
Relative density (D20/4)	1.197	1.196

 

Mean density: 1.196 x 10³ kg/m³

Mean relative density (D20/4): 1.196

Test item temperature: 20.0 ± 0.5 °C

The difference between both determinations was below 20 kg/m³. Therefore, no additional determination was performed.

The heated test item sample with the air bubbles removed which was used in the melting/ freezing point test was also used for this test.

Executive summary:

The density of the test substance was measured under GLP according OECD 109 / EU A3 guideline, using the pycnometer method.

The heated test item sample with the air bubbles removed which was used in the melting/ freezing point test was also used for this test. Two runs were performed. As the difference between both determinations was below 20 kg/m³ , the results were considered as valid and the mean density at 20.0 °C was calculated. This result was then converted to relative density towards water at 4 °C.

Mean density: 1.196 x 10³kg/m³ at 20.0 ± 0.5 °C

Mean relative density (D20/4) : 1.196

Description of key information

The density of the test item has been determined to be1.196 x 10³kg/m³at 20.0 ± 0.5 °C and a relative density (D20/4) of 1.196.

Key value for chemical safety assessment

Relative density at 20C:

1.196

Additional information

A reliable GLP experimental study, conducted according to a recognized OECD/EC method (pycnometer method), is available. It is considered as a key study.