Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-514-3 | CAS number: 2451-62-9
Toxicity to other aquatic organisms
Administrative data
Link to relevant study record(s)
Description of key information
Tests with fish, Daphnia and green algae have been conducted with TGIC showing moderate to low toxicity in the short-term assay.
Long-term tests with these ortganisms are expected to show similar toxicity with the NOEC 2-4 times lower than in the short-term assay. However, as all three organisms showed LC50 or EC50 in the same range, it is to be expected that tests with other aquatic organisms will be in the same range.
In addition, TGIC is rapidly hydrolized in water to form 1,3,5-tris(hydroxypropyl)-1,3,5-triazine-2,4,6-(1H, 3H, 5H)-trion, an alcohol of rather low toxicity as can be expected from other alcohols (phloroglucinol, CAS no. 108-73-6).
Additional information
Based on the low toxicity in fish , Daphnia and algae in fresh-water, and the similarity of the toxicity endpoints, it is expected that tests with other aquatic organisms will lead to the same range of toxicity.
TGIC is rapidly hydrolized in water, and thus aquatic organisms are mainly exposed to the degradation product, 1,3,5-tris(hydroxypropyl)-1,3,5-triazine-2,4,6-(1H, 3H, 5H)-trione. This degradation product is expected to be of low toxicity as it represents an alcohol, and alcohols are generally of low toxicity. Therefore, no other water-borne organisms have been tested.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
