Registration Dossier

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Theready biodegradabilityofthe target compound 2-Benzyl-4-(dimethylamino)butanoic acid was predicted employing three different predictors:BIOWIN module of EPISuite, Toxtree and Vega.

The three predictors were employed in order to apply a weight of evidence (WoE) approach to enhance the reliability of the predictions. In the weight of evidence assessment only reliable predictions are to be taken into account.

In the case of the target compound 2-Benzyl-4-(dimethylamino)butanoic acid, it was predicted as not ready biodegradable by BIOWIN (moderate reliable prediction), as possible readily biodegradable by Vega (moderate reliable prediction), and as persistent by Toxtree (reliability assessment not applicable).

Thus it was concluded that 2-Benzyl-4-(dimethylamino)butanoic acid was predicted as NOT ready biodegradable and the prediction was assessed as moderate reliable.

Additional information

The prediction was provided on the substance2-Benzyl-4-(dimethylamino)butanoic acid (CAS 1613 -23 -6), the acid form of the substance in the object of the registration.