Registration Dossier
Registration Dossier
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EC number: 217-992-8 | CAS number: 2033-24-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vivo
- Type of information:
- other: read across based on OECD Toolbox v3.4
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- see attached OECD Toolbox study
- Guideline:
- other: read across
- GLP compliance:
- not specified
- Species:
- other: rabbit, guinea pig, human
- Strain:
- not specified
- Irritation parameter:
- primary dermal irritation index (PDII)
- Basis:
- mean
- Score:
- 2.8
- Max. score:
- 8
- Reversibility:
- fully reversible
- Remarks on result:
- probability of moderate irritation
- Interpretation of results:
- Category 2 (irritant) based on GHS criteria
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation: in vivo
- Type of information:
- other: read across based on OECD Toolbox v3.4
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- see attached OECD Toolbox study
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- not specified
- Species:
- rabbit
- Strain:
- not specified
- Irritation parameter:
- other: no data
- Basis:
- mean
- Score:
- 0
- Max. score:
- 110
- Reversibility:
- fully reversible
- Remarks on result:
- other: not irritating
- Interpretation of results:
- not irritating
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
At the effect levels found there is no requirement to classify the substance for eye irritation or STOT SE. However, the substance must be classified for skin irritation category 2
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
