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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

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Description of key information

OECD 209 Activated sludge respiration inhibition 3 hour EC50 721 mg/L, EC10 141 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
721 mg/L
EC10 or NOEC for microorganisms:
141 mg/L

Additional information

The toxicity of the test item TOFA_DimerFA_TEPA_PAA (batch no.: BB 000649 V1) to activated sludge was determined in accordance with OECD Test Guideline 209 at Akzo Nobel, Arnhem, The Netherlands.

The toxicity of TOFA_DimerFA_TEPA_PAA to activated sludge was determined at a contact time of 3 hours, using various concentrations of the test substance.


The EC50of TOFA_DimerFA_TEPA_PAA for activated sludge after 3 hours contact time is 721 mg/L. The EC10 and EC20 are 141 and 247 mg/L, respectively.


TOFA_DimerFA_TEPA_PAA is therefore considered not harmful to activated sludge.