Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
Please refer to the category justification provided in the category object.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
(Z)-9-Octadecen-1-ol ethoxylated
EC Number:
500-016-2
EC Name:
(Z)-9-Octadecen-1-ol ethoxylated
Cas Number:
9004-98-2
Molecular formula:
Not applicable: isomeric structures
IUPAC Name:
(Z)-9-Octadecen-1-ol ethoxylated

Results and discussion

In vivo (non-LLNA)

Resultsopen allclose all
Key result
Group:
negative control
Remarks on result:
other: Not sensitising based on all available relevant skin sensitisation data in the Alcohol Ethoxylates (AE) category.
Key result
Group:
test chemical
Remarks on result:
other: Not sensitising based on all available relevant skin sensitisation data in the Alcohol Ethoxylates (AE) category.
Key result
Group:
positive control
Remarks on result:
other: Not sensitising based on all available relevant skin sensitisation data in the Alcohol Ethoxylates (AE) category.

Any other information on results incl. tables

For a detailed assessment of the skin sensitisation potential of the Alcohol Ethoxylates (AE) category, please refer to the category justification attached to the category object.

Applicant's summary and conclusion

Interpretation of results:
other: CLP/EU GHS criteria not met, no classification required according to Regulation (EC) No 1272/2008
Conclusions:
Applying read-across based on grouping of substances (category approach), no skin sensitisation potential is predicted for the target substance.
Executive summary:

The available data on skin sensitisation in the Alcohol Ethoxylates (AE) category indicate no skin sensitisation potential for the target substance. As explained in the category justification, the differences in molecular structure and composition between the target substance and the members of the AE category are unlikely to lead to differences in the skin sensitisation potential.