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Diss Factsheets
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EC number: 918-984-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2004-03-12 to 2004-06-09
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Details on sampling:
- Not applicable
- Vehicle:
- no
- Details on test solutions:
- The mother solution preparation is carried out at a concentration a little bit higher than 100 mg/L.
Dilutions are made in order to obtain concentrations in a geometrical series; that permit to calculate the EC50-48 hours; the concentrations are; 0.6; 1.1; 5.6; 11; 56 and 111 mg/L.
The test item solution has to be prepared immediately before the introduction of Daphnia's. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna Straus aged more than 6 hours and less than 24 hours at the beginning of the test.
Source: U.G. Gent University_laboratory Prof.Persoone. In incubation in the laboratory
Alimentation: Cultivation of Selenastrum capricornutum algae - Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- no post exposure observation period
- Hardness:
- 250 mg/l (in CaCO3)
- Test temperature:
- 21°C ± 1°C.
- pH:
- pH 7.6 (± 0.2)
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Nominal and measured concentrations:
- Nominal concentrations: 0.6; 1.1; 5.6; 11; 56 and 111 mg/L.
- Details on test conditions:
- 20 organisms by test concentration (2 parts of 10).
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 45 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- no data
- Validity criteria fulfilled:
- not specified
- Conclusions:
- After a 48 hours incubation, the immobilisation of 50% Daphnia’s magna appears for a 45 mg/l
concentration.
EC50 48h Daphnia magna : 45 mg/l - Executive summary:
Determination, in the conditions defined in this norm, of the initial concentration (it means the concentration at the beginning of the test) that, in 24 and 48 hours, immobilises 50 % of the Daphnia’s put in experimentation.
This concentration called effective initial inhibitive concentration is designed by EC50-24/48 h.
After a 48 hours incubation, the immobilisation of 50% Daphnia’s magna appears for a 45 mg/l
concentration.
EC50 48h Daphnia magna : 45 mg/l
Reference
Results:
Concentrations | Immobile Daphnia’s after 48 hours | % immobility | |
A | B | ||
Blanc | 0 | 0 | 0 |
0.6 | 0 | 0 | 0 |
1.1 | 0 | 0 | 0 |
5.6 | 0 | 1 | 10 |
11 | 2 | 2 | 40 |
56 | 5 | 6 | 55 |
111 | 10 | 9 | 95 |
Calculation method: Probit method
Description of key information
After a 48 hours incubation, the immobilisation of 50% Daphnia’s magna appears for a 45 mg/l concentration.
EC50 48h Daphnia magna : 45 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- ca. 45 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.