Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The test substance was tested for algae growth inhibition according to OECD guideline No. 201: "Freshwater Alga and Cyanobacteria, Growth Inhibition Test", adopted March 23, 2006; Annex 5 corrected 28 July 2011, and Commission regulation (EC) No. 440/2008 of 30 May 2008, Part C.3: “Algal Inhibition Test”; amended by EC No. 761/2009 of 23 July 2009, Publication No. L220.
The EC50 for growth rate inhibition (72h-ERC50) was 100 mg/L; the 72h-NOEC for growth rate inhibition was 10 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 102.79 mg/L
- EC10 or NOEC for freshwater algae:
- 10 mg/L
Additional information
The toxicity of Lithium salt of branched-aliphatic dicarboxylic acid towards algae was evaluated in a reliable study according to the appropriate standard test methods EU Method C.3 (Algal Inhibition Test) and OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test). Six replicates of exponentially growing algal cultures were exposed to a control, whereas three replicates per concentration were exposed to nominal Lithium salt of branched-aliphatic dicarboxylic acid concentrations of 10, 22, 46, 100 and 220 mg/L. The initial cell density was 104 cells/mL and the total exposure period was 72 hours.
The EC50 for growth rate inhibition (72h-ERC50) was 102.79 mg/L; the EC50 for yield inhibition (72h-EYC50) was 25.60 mg/L; the 72h-NOEC for growth rate inhibition was 10 mg/L; the 72h-NOEC for yield inhibition was <10 mg/L.
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