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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015.3.27-2015.5.13
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to an appropriate OECD test guideline, and in compliance with GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
yes (incl. QA statement)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.24
Temp.:
20 °C
Remarks on result:
other: pH data was not available
Details on results:
Recoveries of Red 620 in octanol phase and water phase were 85.3±3.1%, 83.3±1.3%, respectively and the Relative Standard Deviation (RSD) was less than 20% (Table 1, 2).
LogPow values of Red 620 from the all three runs with the different solvents ratios were 1.28±0.01 (2 mL, test 1), 1.15±0.04 (4 mL, test 2), 1.29±0.00 (1 mL, test 3). The average value of LogPow is 1.24 ± 0.08 (Table 3, Fig 1).

Applicant's summary and conclusion

Conclusions:
The average logPow value from the all three runs with the different solvents ratios was 1.24± 0.08. The variation of partition coefficient calculated with different volume ratio was within ±0.3 logPow. This result was acceptable range specified by the National Institute of Environmental Research, Korea and OECD test guidelines.