Registration Dossier
Registration Dossier
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EC number: 211-049-4 | CAS number: 628-68-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Comparative toxicity of triacetin and diethylene glycol acetate
- Author:
- Nosko, M.
- Year:
- 1 977
- Bibliographic source:
- Problemi na Khigienata (1977)3, 25-34
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 425 (Acute Oral Toxicity: Up-and-Down Procedure)
- Qualifier:
- according to guideline
- Guideline:
- other: Deichmann, W. and Leblanc, T. J. 1943. Determination of the Approximate Lethal Dose with About 6 Animals. Journal of Industrial Hygiene and Toxicology, Vol. 25, pp. 415-417.
- GLP compliance:
- no
- Test type:
- up-and-down procedure
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: gavage
Results and discussion
Effect levelsopen allclose all
- Dose descriptor:
- LDLo
- Effect level:
- 10.7 mL/kg bw
- Based on:
- test mat.
- Dose descriptor:
- LDLo
- Effect level:
- 11 770 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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