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EC number: 262-110-7 | CAS number: 60223-95-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- July 2 - November 9, 1979
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: limited reported test, non-GLP, no information on individual samples, limited in-life and exposure conditions. The test is indicative for a low bioaccumulation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 979
- Report date:
- 1979
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: "Method for Testing the Degree of Accumulation of Chemical Substances in Fish Body" in "Testing Methods for New Chemical Substances" (July 13, 1974), MHW. MITI
- Deviations:
- not specified
- GLP compliance:
- no
Test material
- Reference substance name:
- di C8-C10, branched, C9 rich, alkylnaphthalene disulphonic acid
- IUPAC Name:
- di C8-C10, branched, C9 rich, alkylnaphthalene disulphonic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Physical state: brown powder
Constituent 1
- Radiolabelling:
- no
Sampling and analysis
- Details on sampling:
- - Sampling intervals/frequency for test organisms: every two weeks for 8 weeks
- Sampling intervals/frequency for test medium samples: every two weeks for 8 weeks
- Sample storage conditions before analysis: no data
- Details on sampling and analysis of test organisms and test media samples:
1) test water: after sampling hydrochloric acid and sodium chloride were added, thereafter samples were shaken twice with trioctylmethylammonium chloride in chloroform. The water layer was decanted and the organic fraction was filtrated (dehydration), dried (evaporation), resuspended in methanol and analysed by HPLC
2) fish: fish were weighed and measured before chopped. Thereafter they were suspended in methanol and further homogenized. This procedure was repeated twice. The suspension was filtered after each treatment. The filtrate was eluted via column chromatograpy. The eluate was evaporated (to 20-30 mL). Thereafter deionized water and sodium chloride were added and the sample was shaken with trioctylmethylammonium chloride in chloroform. The water layer was decanted and the organic fraction was filtrated (dehydration), dried (evaporation), resuspended in methanol and analysed by HPLC.
Test solutions
- Vehicle:
- no
- Details on preparation of test solutions, spiked fish food or sediment:
- PREPARATION AND APPLICATION OF TEST SOLUTION: stock solution was prepared in water, 2 g test substance in 2 L. This stock solution was further diluted to obtain the test concentrations
Test organisms
- Test organisms (species):
- other: carp
- Details on test organisms:
- TEST ORGANISM
- Common name: carp
- Strain: not indicated
- Source: not indicated
- Length at study initiation : 10.6 cm
- Weight at termination: 30.7 g
- Description of housing: 100 L tank
- Feeding during test: not indicated
ACCLIMATISATION: at 25 °C for 14 days ; kept in aqueous solution with 10 mg/L chlorotetracycline hydrochloride for 24 hours
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- >= 2 - <= 8 wk
Test conditions
- Test temperature:
- 25 ± 1 °C
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 100L
- Type of flow-through: continuous flow
- Renewal rate of test solution: 575 L/day
- No. of organisms per vessel: No data
TEST MEDIUM / WATER PARAMETERS: no data - Nominal and measured concentrations:
- nominal concentrations: 1 and 0.1 mg/L
measured concentration: at 2, 4, 6, and 8 weeks: 0.947, 0.964, 0.980 and 0.987 mg/L; 0.0962, 0.0961,,0.0953 and 0.0973 mg/L
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- <= 0.19 dimensionless
- Basis:
- whole body w.w.
- Calculation basis:
- other: average over 8 week period
- Remarks on result:
- other: Conc.in environment / dose:1 mg/L
- Type:
- BCF
- Value:
- <= 2 dimensionless
- Basis:
- whole body w.w.
- Calculation basis:
- other: average over 8 week period
- Remarks on result:
- other: Conc.in environment / dose:0.1 mg/L
- Details on results:
- Fish appeared normal
Any other information on results incl. tables
BCF values
Exposure duration |
2 week |
4 week |
6 week |
8 week |
1 mg/L |
≤0.19 |
≤0.19 |
≤0.19 |
≤0.19 |
0.1 mg/L |
≤ 2.0 |
≤ 2.0 |
≤ 2.0 |
≤ 2.0 |
Applicant's summary and conclusion
- Conclusions:
- The bioconcentration factor of the test substance is ≤ 2.0
- Executive summary:
Carp were exposed to the test substance at 1 and 0.1 mg/L in a flow-through test. Analyses of the test water and a sample of the fish were performed after 2, 4, 6, and 8 weeks. The Bioconcentration factor was assessed to be ≤ 0.19 at 1 mg/L and ≤ 2.0 at 0.1 mg/L.
The test substance does not bioaccumulate in fish.
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