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EC number: 247-557-8 | CAS number: 26264-06-2
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Sodium dodecylbenzenesulfonate (CAS# 25155-30-0 , EC Number; 246-680-4 ) is a very close analogue of Calcium dodecylbenzenesulfonate (CAS No 26264-06-2, EC Number; 247-557-8) ) and read-across is valid.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Sodium (linear) dodecylbenzenesulphonate was added to Knudson C medium at concentrations of 10,100 and 1000 ppm.Surface tension (ST) and interfacial tension (IT) values were obtained for sterilizing agar-free Knudson C medium employing a Cento duNouy model 70530, surface tensiometer and a Cenco duNouy, model 70540, interfacial tensiometer.
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Species:
- other: Phalaenopsis cv. Alice Glocia × Phalaenopsis cv.Francine
- Test type:
- other: Motality, Growth effect
- Study type:
- laboratory study
- Substrate type:
- other: Knudson C culture medim(kNUDSON, 1946)
- Limit test:
- no
- Total exposure duration:
- 5 mo
- Test temperature:
- 20-26 deg C
- pH:
- 5.1 +/- 0.2
- Details on test conditions:
- Culture flasks were inoculated with seeding of Phalaenopsis cv. Alice Glocia × Phalaenopsis cv.Francine. Phalaenopsis seedings were maintained in a glasshouse under natural daylight conditions, a maximum of 600 ft-cancles and a temperature range of 20-26 deg C. The pH of culture media was adjust to 5.1 +/- 0.2 proio to autoclaving at 15 lb/in^2 for 20 minutes
- Nominal and measured concentrations:
- 10, 100 and 1000 ppm based on active matter
- Species:
- other: Phalaenopsis cv. Alice Glocia × Phalaenopsis cv.Francine
- Duration:
- 5 mo
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- other: Phalaenopsis cv. Alice Glocia × Phalaenopsis cv.Francine
- Duration:
- 5 mo
- Dose descriptor:
- EC50
- Effect conc.:
- 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- other: Phalaenopsis cv. Alice Glocia × Phalaenopsis cv.Francine
- Duration:
- 5 mo
- Dose descriptor:
- EC100
- Effect conc.:
- 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Details on results:
- Phalaenopsis survived at concentration of 10 ppm with only minimal inhibition. However, LAS was inhibitory at 100 ppm. At concentration of 1000 ppm, LAS was invariably deleterous. There were no survivors in culture of LAS which also exhibited extremely low IT values.
- Validity criteria fulfilled:
- yes
- Conclusions:
- This study showed evidence regarding the inhibitors of growth and decrease in survival caused LAS.
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction:US EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- EPI Suite v 4.1/ECOSARv1.00
- GLP compliance:
- no
- Remarks:
- not applicable. QSAR model
- Analytical monitoring:
- not required
- Vehicle:
- no
- Species:
- other: Terrestrial plants,QSAR model
- Plant group:
- other: QSAR model
- Details on test organisms:
- no further information
- Test type:
- other: QSAR
- Study type:
- other: QSAR
- Substrate type:
- other: QSAR
- Limit test:
- no
- Total exposure duration:
- 30 d
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Moisture:
- not applicable. QSAR model
- Details on test conditions:
- 100%Benzenesulfonic acid, dodecyl-, calcium salt
CAS Number: 26264-06-2
SMILES : CCCCCCCCCCCCc1ccc(S(=O)(=O)OOS(=O)(=O)c2ccc(CCCCCCCCCCCC)cc2)cc1
CHEM : Benzenesulfonic acid, dodecyl-, calcium salt
MOL FOR: C36 H58 O6 S2 Ca1
MOL WT : 691.06
Wat Sol: 0.006264 (mg/L, EPISuite WSKowwin v1.43 Estimate)
Log Kow: 4.770
Remarks: Anionic surfactant – alkyl benzene sulfonates; effective alkyl chain length = C12 - Reference substance (positive control):
- no
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2.736 mg/kg soil dw
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1.266 mg/kg soil dw
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: cited as a ChV value, 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
- Details on results:
- The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 1.266 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 2.736 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same. - Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 1.266 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be2.736 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same. - Executive summary:
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 1.266 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be2.736 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Referenceopen allclose all
Table. Growth effect of LAS on orchid seeding in vitro.
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- IT : Interfacial Tension - ST : Surface tension |
Overview of QSARs estimations on toxicity of
Calcium dodecylbenzenesulfonate/Benzenesulfonic acid, dodecyl-, calcium salt
to terrestrial plants
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Terrestrial plants ,96-hrEC50 = 2.736 mg/L (ppm) Terrestrial plants, 30-day, ChV (chronic value) = 1.266 mg/L (ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
Terrestrial plants ,96-hrEC50 = 2.736 mg/L (ppm)
Terrestrial plants, 30-day, ChV (chronic value) = 1.266 mg/L (ppm)
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Description of key information
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 7.685 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 17.030 mg/L (ppm) for terrestrial plants.
Field studies to terrestrial plants indicate that Sodium dodecylbenzenesulfonate affects the growth and decrease in survival of Orchid (Phalaenopis) (Ernst et al., 1971).NOEC was 10 mg/kg soil.dw and EC50 was 100 mg/kg soil.dw
Three species of crop plant B. rapa, A. sativa, and S. alba, were grown in soil containing concentrations of LAS that varied from 0 -10,000 mg/kg dw soil. The seedlings were grown for 14 days, and then weighed. The weight was compared to weights of controls plants. All three species showed a dose-related reduction in growth.
The EC10 for B. rapa was 86 mg/kg dw soil, for A. sativa it was 80 mg/kg dw soil, and for S. alba it was 200 mg/kg dw soil.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 100 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 10 mg/kg soil dw
Additional information
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 7.685 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 17.030 mg/L (ppm) for terrestrial plants.
Field studies to terrestrial plants indicate that Sodium dodecylbenzenesulfonate affects the growth and decrease in survival of Orchid (Phalaenopis) (Ernst et al., 1971).NOEC was 10 mg/kg soil.dw and EC50 was 100 mg/kg soil.dw
Three species of crop plant B. rapa, A. sativa, and S. alba, were grown in soil containing concentrations of LAS that varied from 0 -10,000 mg/kg dw soil. The seedlings were grown for 14 days, and then weighed. The weight was compared to weights of controls plants. All three species showed a dose-related reduction in growth.
The EC10 for B. rapa was 86 mg/kg dw soil, for A. sativa it was 80 mg/kg dw soil, and for S. alba it was 200 mg/kg dw soil.
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