(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium

Endpoint summary

Additional information

Acute aquatic toxicity

The substance (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium is not considered to be acutely toxic to fish, invertebrates or inhibitory to algal growth as the substance has an acute LL or EL50s of >100 mg/L (WAF), based on read across from a structural analogue.

Published data

The literature search identified no ecotoxicological data for (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium.

Read across

As no data was available for acute toxicity to fish, invertebrates or inhibitory to algal growth of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium, these endpoints were read across from aluminum, benzoate C16-18-fatty acids complexes.

Aluminum, benzoate C16-18-fatty acids complexes (CAS No. 94166-87-7, EC No. 303-385-6) is considered suitable for read-across to (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium as it is structurally similar being an approximate 2:1 mixture of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium and (benzoato-O,O')hydroxy(hexadecanoato-O,O')aluminium. The only significant difference is the presence of about 30% of the aluminium complex containing the saturated C16-fatty acid, hexadecanoate, in place of the saturated C18-fatty acid, octadecanoate. This small difference in composition is expected to have no adverse influence on the acute toxicity to fish and aquatic invertebrates or algal growth.

Proprietary data

Because of the low aqueous solubility, the read-across substance was tested as a Water Accommodated Fraction (WAF). Amounts of test item were added to the surface of the dilutent at the appropriate loading rate. After the addition of the test item, the media was stirred by a magnetic stirrer using a stirring rate such that a vortex was formed to give a dimple at the water surface. The stirring was stopped after 23 hours and the mixture allowed to stand for 1 hour. A wide bore glass tube, covered at one end with Nescofilm was submerged into the vessel, sealed end down, to a depth of approximately 5 cm from the bottom of the vessel. A length of Tygon tubing was inserted into the glass tube and pushed through the Nescofilm seal and the WAFs removed by mid-depth siphoning (the first approximate 75-100 mL discarded) to give the WAF. Microscopic inspection of the WAF showed no micro-dispersions or undissolved test item to be present.

While ensuring that media were compatible with the water chemistry requirements of the test species, the tests on the three taxa were conducted using water from the same source with similar characteristics. As the water solubility of the substance is likely to be influenced by the hardness of the water, the ecotoxicity tests were all conducted in media with the same hardness, approximately 150 mg/L CaCO₃. As the substance could not be analysed directly, both the aluminium and the total organic carbon were measured in the exposure media. The acute toxicity ofaluminum, benzoate C16-18-fatty acids complexes to fish and Daphnia and toxicity to algal growth showed no effects at a water accommodated fraction nominal loading rate of 100 mg/L. Therefore, for fish the 96 hour LL50 is > 100 mg/L (WAF), for Daphnia the 48 hour EL50 is >100 mg/L (WAF) and for algal growth inhibition the 72 hour EL50 is >100 mg/L (WAF). The acute toxicity to fish, Daphnia and toxicity to algal growth were determined in GLP-compliant, limit tests following OECD guidelines 203, 202 and 201 respectively (Harlan 2013).