Registration Dossier
Registration Dossier
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EC number: 611-880-6 | CAS number: 5976-55-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Justification for type of information:
- QSAR prediction
Data source
Reference
- Reference Type:
- other: Predicted data
- Title:
- Unnamed
- Year:
- 2 016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- (17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl acetate
- EC Number:
- 611-880-6
- Cas Number:
- 5976-55-6
- Molecular formula:
- C21H28O3
- IUPAC Name:
- (17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl acetate
- Test material form:
- solid: crystalline
- Details on test material:
- Test item: estradiol-methyl-ether-acetateCAS No.: 5976-55-6Physical state: white crystalline powderStorage:15-30 °C, protected from light and wet
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2.68 mg/L
- Nominal / measured:
- estimated
- Remarks on result:
- other: Database: Aquatic Japan MoE (Pseudokirchneriella subcapitata)
Applicant's summary and conclusion
- Conclusions:
- According to (Q)SAR modell: QSAR Toolbox, the predicted value indicated that estradiol-methyl-ether-acetate is hazardous to algae (Pseudokirchneriella subcapitata). The result meets the requirement of Aquatic Acute Category 2.
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