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Ecotoxicological information

Toxicity to microorganisms

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Link to relevant study record(s)

Reference
Endpoint:
toxicity to microorganisms, other
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from peer-reviewed journal
Justification for type of information:
Data for the target chemical is summarized based on the structurally similar read across chemicals
Reason / purpose:
read-across source
Reason / purpose:
read-across source
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
WoE report is based on two toxicity study of microorganism for the test chemical :
2. and 3. This study was examined to assess the toxic effects of the test compound on the bacteria in a 24 hours of exposure.
GLP compliance:
not specified
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Pseudomonas fluorescens
Test type:
not specified
Water media type:
not specified
Total exposure duration:
24 h
Reference substance (positive control):
not specified
Duration:
24 h
Dose descriptor:
EC0
Effect conc.:
1 000 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
500 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Validity criteria fulfilled:
not specified
Conclusions:
The effective concentration (EC0) value of test material in bacteria was found to be in range of 500- 1000 mg/L in a 24 hours of exposure.
Executive summary:

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:

This study was examined to assess the toxic effects of the test compound on Pseudomonas fluorescens in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be in the range 500- 1000 mg/L.

Description of key information

Toxicity to microorganisms:

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:

This study was examined to assess the toxic effects of the test compound on Pseudomonas fluorescens in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be in the range 500- 1000 mg/L.

Key value for chemical safety assessment

Additional information

Toxicity to microorganisms:

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:

This study was examined to assess the toxic effects of the test compound on Pseudomonas fluorescens in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be in the range 500- 1000 mg/L.