Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-208-9 | CAS number: 93-00-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from peer-reviewed journal
- Justification for type of information:
- Data for the target chemical is summarized based on the structurally similar read across chemicals
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- WoE report is based on two toxicity study of microorganism for the test chemical :
2. and 3. This study was examined to assess the toxic effects of the test compound on the bacteria in a 24 hours of exposure. - GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Pseudomonas fluorescens
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 24 h
- Reference substance (positive control):
- not specified
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 500 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The effective concentration (EC0) value of test material in bacteria was found to be in range of 500- 1000 mg/L in a 24 hours of exposure.
- Executive summary:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:
This study was examined to assess the toxic effects of the test compound on Pseudomonas fluorescens in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be in the range 500- 1000 mg/L.
Reference
Description of key information
Toxicity to microorganisms:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:
This study was examined to assess the toxic effects of the test compound on Pseudomonas fluorescens in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be in the range 500- 1000 mg/L.
Key value for chemical safety assessment
Additional information
Toxicity to microorganisms:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:
This study was examined to assess the toxic effects of the test compound on Pseudomonas fluorescens in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be in the range 500- 1000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
