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EC number: 206-496-7 | CAS number: 350-03-8
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water: Screening tests: readily biodegradable, 85% in 28 days (O2 consumption), 60% in 3 days (EU Method C.4-E / OECD 301 D (Ready Biodegradability: Closed Bottle Test))
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
There is one OECD guideline study on biodegradation in water: screening tests available, assessed with Klimisch 1 and hence considered as sufficiently reliable to cover this endpoint.
3-Acetylpyridine was tested for the ready biological degradability in a Closed Bottle Test according to EEC Directive 92/69/EEC, Annex V, Determination of the Ready Biodegradability, C.4E Closed Bottle Test and OECD guideline 301D.
Within 28 days a degradation of 85 % of 3-Acetylpyridine based on O2 consumption was attained, the value of 60% was reached on the 3rd day.
According to Commission Directive 93/21/EEC, Annex IV, article 5.2.1.3. the substances are considered readily degradable, if in 28-day biodegradation studies the following levels of degradation are achieved:
-in tests based upon dissolved organic carbon: 70% of the theoretical maximum
-in tests based upon oxygen depletion or carbon dioxide generation: 60 % of theoretical maximum
These levels of biodegradation must be achieved within 10 days of the start of degradation, which point is taken as the time when 10% of the substance has been degraded.
According to the above-mentioned criteria, the test substance, 3-Acetylpyridine, is ready biodegradable.
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