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Diss Factsheets

Physical & Chemical properties

Density

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08/10/2015 – 08/10/2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard OECD test guidelines
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Principles of method if other than guideline:
The density is calculated from the difference in weight between the full and empty pycnometer and its volume.
GLP compliance:
no
Type of method:
other: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014
Key result
Type:
pour density
Density:
0.632 g/cm³
Temp.:
30 °C
Key result
Type:
tap density
Density:
0.816 g/cm³
Temp.:
30 °C

Parameters

Details

Calculated Values (RESULT)

Pour Density of test substance (g/cm3)

m
    v

0.6318 g/cm3

Tap density of test substance (g/cm3)

m
    v1

0.8163 g/cm3

Conclusions:
The pour density and tapped density of disodium 4,4'-[[2,4-dihydroxy-5-(hydroxymethyl)-1,3-phenylene]bis(azo)]bisnaphthalene-1-sulphonate (CAS No. 4553-89-3) were determined to be 0.6318 gm/cm3 and 0.8163 gm/cm3 at 29.9 °C and 975.2 hPa, respectively.
Executive summary:

The density of test item disodium 4,4'-[[2,4-dihydroxy-5-(hydroxymethyl)-1,3-phenylene]bis(azo)]bisnaphthalene-1-sulphonate (CAS No. 4553-89-3) was determined following OECD guideline OECD 109 according to pour and tap density method. The pour density and tapped density of the test item were determined to be 0.6318 gm/cm3 and 0.8163 gm/cm3  at 29.9 °C and 975.2 hPa, respectively.

Description of key information

The pour density and tapped density of disodium 4,4'-[[2,4-dihydroxy-5-(hydroxymethyl)-1,3-phenylene]bis(azo)]bisnaphthalene-1-sulphonate (CAS No. 4553-89-3) were determined to be 0.6318 gm/cm3 and 0.8163 gm/cm3 at 29.9 °C and 975.2 hPa, respectively.

Key value for chemical safety assessment

Relative density at 20C:
0.816

Additional information

The density of test item disodium 4,4'-[[2,4-dihydroxy-5-(hydroxymethyl)-1,3-phenylene]bis(azo)]bisnaphthalene-1-sulphonate (CAS No. 4553-89-3) was determined following OECD guideline OECD 109 according to pour and tap density method. The pour density and tapped density of the test item were determined to be 0.6318 gm/cm3 and 0.8163 gm/cm3 at 29.9 °C and 975.2 hPa, respectively.