Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Data waiving (study technically not feasible): The study is technically not feasible since the substance is hydrolytically unstable (half-life < 1h). The Log Koc and Koc of test item should be understood based on its degradation products since it undergoes rapid hydrolysis (half-life < 1h) in water to acetone oxime (log Kow = 1.783 and Koc = 60.7, KOCWIN v2.00) and silanols (Log Kow in the range of 1.642-2.227 and Koc 43.89-168.6 KOWWIN v1.68). Morevoer, it should be pointed out that the corresponding silanols undergo continuous condensation reactions to produce higher molecular weight siloxanes which are considered biologically unavailable. Therefore, the Key value for chemical safety assessment would be the adsorption coefficient of acetone oxime.