Registration Dossier
Registration Dossier
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EC number: 616-020-3 | CAS number: 7381-13-7
Endpoint summary
Administrative data
Description of key information
Skin irritation/skin corrosion: No corrosive or irritant properties
Eye irritation: No corrosive or irritant properties
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
An in vivo study was performed to assess the acute skin irritation/corrosion of the test item. Therefore the
est item was applied, as supplied, at the dose of 0.5 g, under semi-occlusive dressingduring 4 hours on an undamaged skin area of three New Zealand rabbits.
No cutaneous reactions (erythema and oedema) were observed whatever the examination time (1, 24, 48 and 72 hours).
An in vivo study was performed to assess the acute eye irritation/corrosion of the test item.
The ocular conjunctivae reactions observed during the study have been slight and rapidly reversible in the three animals: a slight redness was noted only 1 hour after the test item instillation assoeiated a slight chemosis in two animals only 1 hour after the test item instillation.
Justification for classification or non-classification
not to be classified according to directive EC No. 1272/2008.
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