Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
flammability
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Qualifier:
according to guideline
Guideline:
EU Method A.12 (Flammability (Contact with Water))
Qualifier:
according to guideline
Guideline:
EU Method A.13 (Pyrophoric Properties of Solids and Liquids)
Version / remarks:
Expert statement
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(3R)-N-[(1S)-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazol-3-amine hydrochloride
EC Number:
812-024-6
Cas Number:
1638534-24-3
Molecular formula:
C20H23ClN2
IUPAC Name:
(3R)-N-[(1S)-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazol-3-amine hydrochloride

Results and discussion

Pyrophoric solids
Test procedure:
ignition time on contact with air
Remarks:
Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).
Remarks on result:
no ignition on contact with air (not further specified)
Remarks:
corresponding to 'no' in migrated source record. | Remarks: The TS melted when approached by the ignition flame. The TS propagated burning of the powder train in 8 minutes | Additional remarks: The TS melted when approached by the ignition flame. The TS propagated burning of the powder train in 8 minutes
Pyrophoric liquids
Test procedure:
ignition time on contact with air
Remarks:
Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).
Remarks on result:
no ignition on contact with air (not further specified)
Remarks:
corresponding to 'no' in migrated source record. | Remarks: The TS melted when approached by the ignition flame. The TS propagated burning of the powder train in 8 minutes | Additional remarks: The TS melted when approached by the ignition flame. The TS propagated burning of the powder train in 8 minutes
Substances / mixtures which in contact with water emit flammable gases
Remarks on result:
no reaction with water observed
Remarks:
corresponding to 'no' in migrated source record.| Remarks:The TS did not liberate gases in hazardous amounts as defined in guideline A. 12. The TS did not emit ignitable gases on contact with water. | Additional remarks: The TS did not liberate gases in hazardous amounts as defined in guideline A. 12. The TS did not emit ignitable gases on contact with water.

Applicant's summary and conclusion

Interpretation of results:
non flammable
Remarks:
Migrated information
Conclusions:
Flammable solid; A.10 - No
Liberates flammable gases in contact with water; A.12 - No
Pyrophoric substance; A.13 - No
Expert Statement: Test A.13 not conducted. Experience in production or handling shows that the TS does not liberate flammable gases in contact with water and does not ignite spontaneously on coming into contact with air at normal temperatures (i.e. the TS is known to be stable at room temperature for prolonged periods of time)