Registration Dossier

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Aliphatic Alcohols and Alkyl Esters: Narcotic and Lethal Potencies to Tadpoles and to Rabbits
Author:
Munch, J.C.
Year:
1972
Bibliographic source:
Ind. Med. 41, 31 - 33

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Acute oral toxicity, no further details
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
no data

Administration / exposure

Vehicle:
not specified
Details on study design:
Observation period: 24 hours

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 027 mg/kg bw
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data
Other findings:
no data

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The acute oral toxicity of the test item with rabbits was determined. The LD50 value was determined to be 2027 mg/kg bw.
Executive summary:

The acute oral toxicity of the test item was determined. The publication is classified as disregarded study with insufficient documentation for assessment. A LD50 value (rabbits) of 2027 mg/kg bw was determined.