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Diss Factsheets
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EC number: 434-880-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Study conducted to GLP and in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not effect the quality of the relevant results.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 34 g/L
- Temp.:
- 20 °C
- pH:
- >= 8.7 - <= 8.9
- Remarks on result:
- other: It is evident from the chromatography that a small amount of oxidation had occured even though precautions to minimise oxygen were taken.
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of the test item has been determined to be 34.0g/l at 20 ± 0.5°C - Executive summary:
Method
The determination was carried out using the flask method designed to be compatible with Method A6 Water Solubility of Commission Directive 92/69/EEC.
Conclusion
The water solubility of the test item has been determined to be 34.0 g/l at 20 ± 0.5 °C.
Reference
Results
Preliminary test:
The preliminary estimate of water solubility was 36.9 g/L at 20.0°C.
Definitive test :
Mean peak areas relating to standard and sample solutions
Solution |
Mean peak area |
Standard 251 mg/l |
3.754 X 105 |
Standard 251 mg/l |
3.620 X 105 |
Sample 1A |
2.590 X 105 |
Sample 1B |
2.571 X 105 |
Sample 2A |
2.372 X 105 |
Sample 2B |
2.490 X 105 |
Sample 3A |
2.438 X 105 |
Sample 3B |
2.531 X 105 |
Concentration (g/l) of test material in the sample solutions
Sample number |
Time shaken at 30°C (hours)
|
Time equilibrated at 20°C (hours)
|
Concentration (g/l) |
Solution pH |
1 |
24.25 |
24 |
35.1 |
8.9 |
2 |
48.25 |
24 |
33.1 |
8.9 |
3 |
72.25 |
24 |
33.8 |
8.7 |
Mean concentration : 34.0g/l at 20 ± 0.5 ºC
Range : 33.1 to 35.1 g/l
Description of key information
The water solubility of the test item has been deterimed to be 34.0g/l at 20 ± 0.5°C
Key value for chemical safety assessment
- Water solubility:
- 34 g/L
- at the temperature of:
- 20 °C
Additional information
Method
The determination was carried out using the flask method designed to be compatible with Method A6 Water Solubility of Commission Directive 92/69/EEC.
Conclusion
The water solubility of the test item has been determined to be 34.0 g/l at 20 ± 0.5 °C.
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