Registration Dossier
Registration Dossier
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EC number: 940-005-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Acute oral toxicity:
The test substance was tested for acute oral toxicity in rats according to OECD guideline 423 (Acute Toxic Class Method) under GLP. The substance was administered to three female animals via gavage at the limit dose of 2000 mg/kg bw in a first experiment. As no mortality occured, a second group of three females was treated with the same dose. The mean body weight of the test groups increased throughout the study period within the normal range with one exception in the second test group. One female showed stagnation of body weight during the second week. No mortality or clinical signs were observed. Gross pathology revealed no macroscopic pathological findings in the animals sacrificed at the end of the observation period.
Justification for classification or non-classification
The oral NOAEL was found to be >2000 mg/kg bw in rats. No classification for acute dermal toxicity according to Regulation (EC) No 1272/2008 (CLP) is required.
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