Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Using ECOSAR, the 48-h LC50 is estimated to be 119 mg/l in aquatic invertebrates

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
119 mg/L

Additional information

Due to the fact that vinyl chloride is a gas, no significant concentrations are present in the fresh water and seawater compartment. This is supported by exposure assessment with EUSES. A regional PEC in fresh surface water of 4.18E-06 mg/L and a regional PEC in seawater of 3.44E-07 mg/L were calculated. The maximal local PEC value that was calculated for fresh water was 3.65E-02 mg/L (for S-PVC production). The maximum local PEC value that was calculated for seawater was 3.65E-03 mg/L (for S-PVC production). Since these concentrations are very low, no significant exposure of aquatic invertebrates is assumed and therefore short term toxicity tests with aquatic invertebrates are not considered necessary.

Multiple tests with fish demonstrate a low aquatic toxicity. ECOSAR calculations indicate that there is no significant difference in sensitivity between fish and aquatic invertebrates for vinyl chloride.

Only a QSAR value is available for short-term toxicity in invertebrates. This value will be used in the assessment.