Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-903-6 | CAS number: 255830-15-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- The study was conducted in accordance with OECD 107 but full details are not available.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- not specified
- Key result
- Type:
- log Pow
- Partition coefficient:
- -4.3
- Temp.:
- 20 °C
- Remarks on result:
- other: A pH value of 10 is assumed for the test substance
- Conclusions:
- A log Kow -4.3 (Pow = 4.92E-05) at 20°C was determined for ATMP-N-Oxide-5k using a relevant test method. The result is considered to be reliable.
Reference
Octanol/water ratio |
Test No |
Octanol concentration mg/mL |
Water concentration mg/mL |
Pow |
Average on two values |
A |
1 |
0.00697 |
99.50 |
7.00E-05 |
6.00E-05 |
|
2 |
0.00497 |
99.42 |
5.00E-05 |
|
B |
1 |
0.00448 |
99.45 |
4.50E-05 |
5.50E-05 |
|
2 |
0.00646 |
99.36 |
6.50E-05 |
|
C |
1 |
0.00348 |
99.30 |
3.50E-05 |
3.25E-05 |
|
2 |
0.00298 |
99.32 |
3.00E-05 |
Average value of three determinations : Pow = 4.92E-05
log Kow = -4.3
Description of key information
log Kow (ATMP-N-Oxide-5K): -4.3 (OECD 107)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -4.3
- at the temperature of:
- 20 °C
Additional information
A measured log Kow value of -4.3 at 20°C was determined for the potassium salt of ATMP-N-Oxide according to OECD Test Guideline 107. The result is considered to be reliable and is selected as key study.
This value is supported by a predicted log Kow value of -4 ± 1 which was determined for the parent acid (ATMP-N-oxide-H) using a validated estimation method.
ATMP-N-Oxide-5K is freely soluble in water and, therefore, the ATMP-N-Oxide anion is fully dissociated from its potassium cations when in solution. The ATMP-N-Oxide anion has six P-OH groups that can be ionised. They lose a hydrogen to form a negatively charged group (P-O-). As the pH increases, the number of ionised groups increases. Under any given conditions, the degree of ionisation of the ATMP-N-Oxide species is determined by the pH of the solution. At a specific pH, the degree of ionisation is the same regardless of whether the starting material was ATMP-N-Oxide-5K, ATMP-N-Oxide-H, or another salt of ATMP-N-Oxide.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.