Registration Dossier

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
other: case report
Adequacy of study:
supporting study
Study period:
2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: published data, single data

Data source

Reference
Reference Type:
publication
Title:
A Case of Occupational, Allergic Contact Dermatitis from Diethyl-amino-ethyl Methacrylate (DEMA)
Author:
Higashi, J.
Year:
2003
Bibliographic source:
Skin Research, 2: 414-417, 2003

Materials and methods

Type of sensitisation studied:
skin
Study type:
case report
Test guideline
Qualifier:
no guideline required
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid

Method

Type of population:
occupational
Ethical approval:
not applicable
Subjects:
A 36-year-old Japanese that handled DEMA in his working place.
Clinical history:
- Symptoms, onset and progress of the disease and exposure history:
The person concerned/ affected was exposed to DEMA from Jan. 7, 2002. He noticed pruritus on his hands at midnight of Jan. 19. Edematous erythema developed on his both hands on the morning of Jan. 20. He consulted his neighboring physician and took sick leave until Jan. 24. He returned to work on Jan. 25 using new vinyl gloves. He handled DEMA again on Feb. 21. On the next morning, edematous erythema appeared again on his both hands. He consulted to Kashiwara municipal hospital where he passed a precise medical examination.
Controls:
Not applicable

Results and discussion

Results of examinations:
RESULT OF CASE REPORT:
It was proved by patchtest that the allergic reactions that a 36 year old Japanese man experienced while handling DEMA at his working place are caused indeed by DEMA.

Applicant's summary and conclusion