Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-769-8 | CAS number: 150-76-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Growth inhibition test on Tetrahymena pyriformis - 40 hours: EC50=171.4 mg/l
OECD 301C (100 mg/l of PMP, 30 mg/l of activated sludge): 86% degradation in 28 days based on BOD and 99% based on TOC removal. 100 mg/l can be used as a NOEC.
Key value for chemical safety assessment
Additional information
Two data of reliability 2 are referenced for toxicity to microorganisms:
- the first one (Schultz TW, 1997), reports the results of a tetratox test with Tetrahymena pyriformis under static conditions. Based on nominal test material concentration, an 40 hours IGC50 (Inhibitory Growth Concentration) was calculated to be 171.4 mg/L.
- the second one (Ribo and Kaiser, 1983), reports the light emission reduction of the marine bacteria Vibrio fischerii (former Photobacterium phosphoreum) in a microtox test. It led to 30 min EC50= 4.6 mg/L, 15 min EC50= 4.3 mg/L and 5 min EC50= 3.7 mg/L, based on nominal test material concentration.
Only data from ciliate growth inhibition tests, and specially with T. pyriformis, are relevant for the risk assessment for STPs.
The data from the OECD 301C available on the paramethoxyphenol can also be used : since in the conditions of this test, PMP has been demonstrated to be readily biodegradable, the concentration to which PMP has been tested can be used as a NOEC value, ie 100 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
