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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
3.67 mg/L

Additional information

No toxicity studies have been carried out on microorganisms with registration substance. Composition information, derived using two dimensional gas chromatography, has been used in conjunction with the PETROTOX model v 3.06 to calculate this endpoint.

 

The aquatic toxicity was estimated using the PETROTOX computer model, which combines a partitioning model (used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading) with the Target Lipid Model (used to calculate acute and chronic toxicity of non-polar narcotic chemicals). PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a petroleum substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

  The model predicted an LL50 of > 1000 mg/L and a EL10 of 3.67 mg/L.

QSAR predictions on toxicity to microorganisms of VHGO have also been provided to support the read-across from VHGO to registration substance.