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There are no reliable experimental data on bioaccumulation for p-cresol available. Therefore, data of the isomer m-cresol and o-cresol are taken into account to describe the potential for bioaccumulation of p-cresol based on a read-across approach. The lowest value of 10.7 is used for assessment.

Bioconcentration factors (BCF) in fish (Leuciscus idus melanotus) were determined with 14C-labelled m-cresol. The fish were exposed to a 0.05 mg/l solution of the tests compound. After the test period of 3 days radioactivity was measured in water medium and fish. BCF values of 20 were obtained. In a flow-through test according to OECD guideline 305 E for o-cresol a BCF of 10.7 in zebrafish (Brachydanio rerio) were obtained.

Based on the results it is considered that p-cresol has no potential for bioaccumulation.