Registration Dossier
Registration Dossier
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EC number: 268-500-3 | CAS number: 68109-88-6
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- In accordance with point 8.8.1 of column 1 (Standard Information Required), Annex VIII of REACH (Regulation EC No. 1907/2006), an assessment of the toxicokinetic behaviour of the substance is performed to the extent that can be derived for the relevant available information. Testing for this endpoint is not required as an assessment of the basic toxicokinetic behaviour of the substance has been performed using the available physical-chemical and toxicological data available. Based on the available information, moderate absorption following oral administration is assumed, but it is estimated to be less absorbed following dermal exposure, and completely absorbed following inhalation. The substance is considered to be widely distributed within the body, hardly metabolised, and excreted mainly unchanged in the faeces. Any further testing would not provide any useful information that would assist in refining the risk assessment of this substance.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
