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EC number: 233-020-5 | CAS number: 10022-31-8
A read across approach was followed to cover this endpoint, using the activated sludge respiration inhibition study with BaCl2 performed by Egeler et al. (2010). Based on initially measured total Ba-levels in the water column, a 3-h IC50 and 3-h NOEC of > 622 and >= 622 mg Ba/L, respectively, was reported, corresponding to > 943.1 and >= 943.1 mg BaCl2/L, respectively. This result was recalculated to barium dinitrate based on the barium content of both substances (i.e. > 1881,8 and >= 1181,8 mg barium trinitrate/L).
One key study for the read across substance barium chloride was identified and included in this dossier. In the study from Egeler et al. (2010) it was demonstrated that the test item (BaCl2) did not inhibit respiration of activated sludge at a nominal concentration of up to 1000 mg/L. The total fraction of barium in the test medium was measured at the start of the test. At a nominal concentration of 1000 mg BaCl2/L, the measured total barium content was 622 mg Ba/L (equivalent to 943.1 mg BaCl2/L). Therefore, the 3-h IC50 and 3-h NOEC were > 622 and >= 622 mg Ba/L, respectively.
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