Registration Dossier
Registration Dossier
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EC number: 938-639-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Tests on three trophic levels (fish, daphnia and algae) are available.
Fish (10/concentration) were exposed to the test substance during 96 hours at concentrations of nominal: 0, 10, 20, 40, 60, 80 and 100% of saturation (loading rates: 0, 15, 30, 60, 90, 120 and 150 mg/L. measured TWA: <LOD , 0.276, 0.694 , 1.82 , 2.52, 4.61, and 6.06 mg/L). No mortality or abnormal behaviour was observed at 0, 10 and 20%. In all other concentrations all fish died before the 72 hours observation. The LC50 based on measured concentrations is 0.77 mg/L (loading rate between 30 and 60 mg/L).
Daphnids were exposed to concentrations (WAFs) of the test item of 10, 18, 32, 56 & 100 mg/L. The No Observed Effect Loading Rate (NOEL) was 56 mg/L (measured TWA 5.34 mg/L) and the Lowest Observed Effect Loading Rate (LOEL) was 100 mg/L (measured TWA 8.44 mg/L).
The ERC50 for algae is > 100 mg/L as loading rate and the NOEL is found to be 100 mg/L (measured TWA 3.5 mg/L).
The starting point for the aquatic risk assessment is the LC50 from the fish study. The validity of this study (Klimisch score 2) is lower than the validity of both other studies. However, the outcome clearly represents a worst case. The fish species tested seems to be most vulnerable to effects of the substance.
The substance was tested in a respiration inhibition test according to OECD 209 during 3 hours. No effects on respiration were seen at 1000 mg/L. Therefore it was concluded that the EC50 is > 1000 mg/L (NOEC 1000 mg/L).
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