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Description of key information

The test substance is hydrolitically stable at pH 7

Key value for chemical safety assessment

Half-life for hydrolysis:
11 d
at the temperature of:
25 °C

Additional information

A hydrolysis test was performed following the OECD 111 guideline and EEC C7 guideline under GLP. The hydrolysis of the test item was performed at 50.2 °C ± 0.0 °C at each of pH 4.0, pH 7.0 and pH 9.0. The test substance was found to be stable at pH 7.0 and 50°C . Therefore no further testing was performed at this pH-value. The test substance was not stable at pH 4.0 and at pH 9.0, further testing was performed at elevated temperatures in order to calculate the rate constant (k25) and the half-life time of the hydrolysis at pH 7.0 and pH 9.0 at 25°C.

At pH 4.0, the test susbstance has a half-life time of 254 hours (11 days) at 25°C. The test susbstance is stable at pH 7.0, its half-life lime is longer than one year at 25°C. At pH 9.0, the test susbstance has a half-life time of 8331 hours (347 days) at 25°C.