Registration Dossier
Registration Dossier
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EC number: 436-060-3 | CAS number: - FC 84508 PK
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From April 23, 2001 to May 16, 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- < 0 hPa
- Remarks on result:
- not determinable
- Test no.:
- #1
- Temp.:
- 50 °C
- Vapour pressure:
- < 0 hPa
- Remarks on result:
- not determinable
- Conclusions:
- Under the test conditions, the vapour pressure of the test substance was determined to be <10(-6) hPa at 20 °C
- Executive summary:
A study was performed to determine the vapour pressure of test substance according to OECD Guideline 104 and EU Method A.4. in compliance with GLP using effusion method.
The vapour pressure was measured for two different sample preparations:
1. For purifying of the test substance the water content was removed by treating the sample at 50 ± 5 °C under vacuum (app. 10-3 hPa) for 24 h (mass loss: 0.1 weight %),
2. For purifying of the test substance the water content was removed by treating the sample at 50 ± 5 °C under vacuum (app. 10-3 hPa) for 24 h (mass loss: 0.1 weight %) and the test substance was degassed over night at 70 °C under high vacuum at app. 10-6 hPa, for 12 h.
For the determination of the final vapour pressure the second measurement with the two step purifying process was used.
Under the test conditions, vapour pressure of test substance was determined to be <1.0 x 10-6 hPa at 20 °C.
Reference
The vapour pressure was measured in the temperature range of 29 to 121 °C. No signal was observed in the range 29 to 62 °C, this means the vapour pressure in this range was below the lower detection limit 10-6 hPa. Above this temperature a vapour pressure could be measured.
Description of key information
Vapour pressure of test substance was determined to be <0.000001 hPa at 20 °C
Key value for chemical safety assessment
Additional information
The vapour pressure of test substance was determined according to OECD guideline 104 and EU method A.4 using the effusion method.
The vapour pressure of test substance was determined to be <0.000001 hPa at 20 °C (Smeykal H, 2001).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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