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EC number: 240-383-3 | CAS number: 16291-96-6 An amorphous form of carbon produced by partially burning or oxidizing wood or other organic matter.
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The octanol-water partioning coefficient (log Pow) of charcoal was determined using the HPLC method following OECD guideline No. 117 respectively EU-method A.8 in compliance with the principles of GLP. The determined log Pow values for the 3 charcoal samples were < 0.3 > 1.440; < 0.3; and <0.3 > 1.474 for charcoal (Probe 1: C-Fix = 73.3%), (Probe 2: C-Fix = 80.5%), and (Probe 3: C-Fix = 88.7%), respectively.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.474
- at the temperature of:
- 20 °C
Additional information
The octanol-water partitioning coefficient (log Pow) of charcoal was determined using the HPLC method following OECD guideline No. 117 respectively EU-method A.8 in compliance with the principles of GLP. The determined log Pow values for the 3 charcoal samples were < 0.3 > 1.440; < 0.3; and <0.3 > 1.474 for charcoal (Probe 1: C-Fix = 73.3%), (Probe 2: C-Fix = 80.5%), and (Probe 3: C-Fix = 88.7%), respectively.
Due to the limited solubility of the test item in the solvent, an extract instead of a solution was used for the measurements. Therefore, the results are necessarily related to the used charcoal extracts (charcoal (Probe 1: C-Fix = 73.3%), (Probe 2: C-Fix = 80.5%), and (Probe 3: C-Fix = 88.7%)
with nominal concentrations of round 210000 to 230000 mg/L in methanol/water (75/25 % v/v) under the testing conditions (temperature = 25+1°C, pH = 5.5).
Variations in the retention times of reference items and test item are very small. Therefore a stable configuration of the HPLC-column can be assumed. No observations were made which might give doubts concerning the validity of the results obtained in this study.
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