Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-806-2 | CAS number: 110-82-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Cyclohexane is readily biodegradable, showing 77% biodegradation in 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Two biodegradation studies are available for cyclohexane. The Exxon (1995) study is GLP compliant and follows OECD guideline 301F (Manometric Respiration Test). Non-adapted activated sludge from a domestic sewage treatment plant was exposed to 34 mg/L cyclohexane for 29 days. Biodegradation reached 10% on day 13 and 60% on day 21, with 77% biodegradation by day 29. The Exxon (1995) is the key study in the EU RAR (2004) for cyclohexane; it follows standard guidelines, fulfils the validity criteria and is GLP compliant. There are conflicting results from other studies reported in the EU RAR, however these studies were found to be unreliable for various reasons. Following OECD 301F, 77% degradation of the test material was observed after 28 days with the 10 day window met and therefore cyclohexane is considered to be readily biodegradable.
The BASF (2002) study is a biodegradability in the CO2 headspace test following ISO 14593, though no information is available on whether it was conducted under GLP. Non-adapted activated sludge from a laboratory wastewater treatment plant treating municipal sewage was exposed to 23 mg/L cyclohexane for 49 days. The BASF study (2002) reports a biodegradation of < 10 % after 28 days and 60 to 70 % after 49 days, indicating that cyclohexane was biodegradable under the test conditions but did not fulfil the OECD criteria for ready biodegradability.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
