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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1956
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original study cited not available for review. Included for completion only using information from a secondary source.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Ethyl acetate SIDS initial assessment profile.
Year:
2004
Bibliographic source:
OECD SIAM 14, Paris, 2002
Report date:
2002
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1956

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Acute Oral Toxicity method, no further details available
GLP compliance:
no
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl acetate
EC Number:
205-500-4
EC Name:
Ethyl acetate
Cas Number:
141-78-6
Molecular formula:
C4H8O2
IUPAC Name:
ethyl acetate
Details on test material:
- Name of test material (as cited in study report): No data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
5 620 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Executive summary:

In a study for which only the results are available, an acute oral LD50 value of 5620 mg/kg for ethyl acetate in the rat was reported.