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Physical & Chemical properties

Nanomaterial dustiness

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Administrative data

Endpoint:
nanomaterial dustiness
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with national standards DIN 55992-1:2006 ("Determination of a parameter for the dust formation of pigments and extenders - Part 1: Rotation method"), modified Heubach method

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: DIN 55992-1:2006 (Determination of a parameter for the dust formation of pigments and extenders – Part 1: Rotation method)
Principles of method if other than guideline:
- Principle of test:
The modified Heubach procedure was applied. In the process, the substance sample is mechanically stressed in a rotating drum (dust generation device), and both the dust already contained in this sample and the dust generated due to abrasion are removed from the dust generation device by an air current. The proportion of dust separated and considered as dust with the ability to become airborne is fed into a seven-stage cascade impactor connected to the dust generation device. Particle size classification is conducted by subsequent weighing of the respective dust masses deposited on the individual cascade stages reflecting certain particle size ranges. The “total dustiness” value is determined as the ratio of the mass of removed dust to the total sample mass initially weighed in.

GLP compliance:
no
Type of method:
rotating cylinder
Sampling:
- Sampling procedure: In the seven-stage cascade impactor used here the dust was separated into 7 fractions between approx. 0.3 µm and 30 µm.
- Measurement procedure: A scale with a resolution of 0.01 mg (Shimadzu AUW-220D, D-K-17702-01-00) was used to determine the mass of deposited quantities of dust on the individual impactor stages.
- Sample size: 1.04 g

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Barium carbonate HP BM 020
- Physical state: solid, white powder

Results and discussion

Dustiness index
Mean:
241 720 mg/kg
Remarks on result:
other: St. dev. not reported

Any other information on results incl. tables

Table 1: Experimental results

Quantity of substance used [g]

1.04088

Mass Median Aerodynamic Diameter (MMAD) [µm]

20.1

Geometric Standard Deviation (GSD) [µm]

3.4

Total dustiness [mg/g]

241.72

Inhalable fraction [mg/g]

160.74

Thoracic fraction [mg/g]

86.74

Respirable fraction [mg/g]

30.73

 

Applicant's summary and conclusion

Conclusions:
Total Dustiness (airborne fraction) measured by using the modified Heubach procedure showed a total dustiness value of 241.72 mg/g for Barium Carbonate BM020.
Executive summary:

Total Dustiness (airborne fraction): 241.72 mg/g.

Mass median aerodynamic diamater of airborne fraction: MMAD = 20.10 µm (distribution fitted to cascade impactor data). Geometric standard deviation of MMAD (GSD) = 3.40.