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EC number: 208-167-3 | CAS number: 513-77-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Nanomaterial dustiness
Administrative data
- Endpoint:
- nanomaterial dustiness
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Test procedure in accordance with national standards DIN 55992-1:2006 ("Determination of a parameter for the dust formation of pigments and extenders - Part 1: Rotation method"), modified Heubach method
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 55992-1:2006 (Determination of a parameter for the dust formation of pigments and extenders – Part 1: Rotation method)
- Principles of method if other than guideline:
- - Principle of test:
The modified Heubach procedure was applied. In the process, the substance sample is mechanically stressed in a rotating drum (dust generation device), and both the dust already contained in this sample and the dust generated due to abrasion are removed from the dust generation device by an air current. The proportion of dust separated and considered as dust with the ability to become airborne is fed into a seven-stage cascade impactor connected to the dust generation device. Particle size classification is conducted by subsequent weighing of the respective dust masses deposited on the individual cascade stages reflecting certain particle size ranges. The “total dustiness” value is determined as the ratio of the mass of removed dust to the total sample mass initially weighed in. - GLP compliance:
- no
- Type of method:
- rotating cylinder
- Sampling:
- - Sampling procedure: In the seven-stage cascade impactor used here the dust was separated into 7 fractions between approx. 0.3 µm and 30 µm.
- Measurement procedure: A scale with a resolution of 0.01 mg (Shimadzu AUW-220D, D-K-17702-01-00) was used to determine the mass of deposited quantities of dust on the individual impactor stages.
- Sample size: 1.04 g
Test material
- Reference substance name:
- Barium carbonate
- EC Number:
- 208-167-3
- EC Name:
- Barium carbonate
- Cas Number:
- 513-77-9
- Molecular formula:
- BaCO3
- IUPAC Name:
- barium carbonate
- Test material form:
- solid: nanoform
Constituent 1
Results and discussion
Dustiness index
- Mean:
- 241 720 mg/kg
- Remarks on result:
- other: St. dev. not reported
Any other information on results incl. tables
Table 1: Experimental results
Quantity of substance used [g] |
1.04088 |
Mass Median Aerodynamic Diameter (MMAD) [µm] |
20.1 |
Geometric Standard Deviation (GSD) [µm] |
3.4 |
Total dustiness [mg/g] |
241.72 |
Inhalable fraction [mg/g] |
160.74 |
Thoracic fraction [mg/g] |
86.74 |
Respirable fraction [mg/g] |
30.73 |
Applicant's summary and conclusion
- Conclusions:
- Total Dustiness (airborne fraction) measured by using the modified Heubach procedure showed a total dustiness value of 241.72 mg/g for Barium Carbonate nano
- Executive summary:
Total Dustiness (airborne fraction): 241.72 mg/g.
Mass median aerodynamic diamater of airborne fraction: MMAD = 20.10 µm (distribution fitted to cascade impactor data). Geometric standard deviation of MMAD (GSD) = 3.40.
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