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Toxicity to microorganisms

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Key value for chemical safety assessment

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In a key static 4-day Photobacterium phosphoreum luminescence inhibition study (KS=2) using other lubricant base oils as control substances, no significant luminescence inhibition was observed for Spindle oil (BP 320-400 ºC) and Neutral oil Ro NIII (BP 400-450 ºC), as well as for the n-paraffin dodecane. The actual NOEL for Spindle oil was > 1.93 mg/L and the actual NOEL for Neutral oil Ro NIII was > 2.17 mg/L (Riis et al., 1996).

The results of computer modelling to estimate aquatic toxicity show no acute toxicity of other lubricant base oils to aquatic microorganisms at or below its maximum attainable water solubility (Redman et al., 2010b). This supports the Riis et al. 1996 experimental results mentioned in the previous paragraph.