Registration Dossier
Registration Dossier
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EC number: 476-160-4 | CAS number: 54807-34-0
Endpoint summary
Administrative data
Description of key information
Additional information
Two aquatic toxicity studies were carried out on NaDMH: Short term toxicty to Daphnia and Toxicity to microorganisms.
The NaDMH study carried out on Daphnia gave a 48 hour EC50 of greater than 100 mg/L. Correspondingly the No Observed Effect Concentration was 100 mg/L. The effect of NaDMH on the respiration of activated sewage sludge gave a 3-hour EC50 of 2200 mg/L. The NOEC after 3 hours exposure was 320 mg/L.
The remaining aquatic toxicity studies were conducted on the analogue chemical DMH.
A study is available which was performed with rainbow trout according to EPA Guideline 72-1. DMH was tested at a nominal concentration of 1000 mg/L . The measured concentration of DMH was 972.2 mg/L. No mortalities occurred. The LC50 was therefore determined to be > 972.2 mg/L.
As previously stated all but two of these studies have been performed on DMH (Dimethyl Hydantoin) and have been used for read-across purposes. A summary of data for read-across of NaDMH with DMH is given in Section 13.
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