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Description of key information

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

The data after treatment by gavage show that nearly the entire amount of the labelled test substance applied was excreted. Most of the radioactivity was found in the feces and only a small extend was found in the urine. The residual radioactivity found in the blood and in the homogenized rat carcasses was very small.

The data after intravenous treatment show that some radioactivity was eliminated by feces and by urine, but distinctively slower than after oral application. Whereas the residual radioactivity found in the blood was also very small, the majority of the residual radioactivity was found in the homogenised rat carcasses (74 %).

The data collected show that both the resorption by the intestinal tract and the excretion of resorbed test substance via the bile or the renal way occur relatively slowly. They show also that there is no accumulation of test substance given orally.