Registration Dossier
Registration Dossier
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EC number: 208-915-9 | CAS number: 546-93-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
Magnesium carbonate is an inorganic ionic solid and is expected to partition strongly to water rather than organic media. Given the physico-chemical properties of magnesium carbonate, it is expected that the substance would not penetrate the skin in any significant quantity and hence skin sensitisation following exposure is considered to be unlikely. Furthermore, magnesium carbonate is an approved ingredient of cosmetics for topical application to skin.
Migrated from Short description of key information:
No laboratory animal studies are available, but human experience indicates magnesium carbonate is not a skin sensitiser.
Justification for classification or non-classification
Skin sensitisation to magnesium carbonate is considered to be unlikely due to the inorganic nature of the substance limiting absorption through the skin and its approved usage in cosmetics. Therefore, magnesium carbonate does not require classification according to the criteria described in Regulation (EC) No 1272/2008.
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