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EC number: 208-915-9 | CAS number: 546-93-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No studies are available on magnesium carbonate.
The acute toxicity of magnesium chloride hexahydrate to algae has been investigated in a GLP study performed in accordance with OECD Test Guideline 201. The test was performed as a limit test using 100 mg/L. The 72 h NOEC was 100 mg/L and the EC50 was >100 mg/L. The results from this study can be read across to magnesium carbonate and hence the equivalent 72 h EC50 is >65 mg MgCO3/L and the NOEC is 65 mg MgCO3/L.
Key value for chemical safety assessment
Additional information
Rationale for read across:
Magnesium chloride hexahydrate is significantly more soluble in water than magnesium carbonate and therefore represents the worst case in terms of bioavailability in natural waters. Although magnesium carbonate is less soluble, both magnesium chloride hexahydrate and magnesium carbonate are expected to dissociate to their ionic forms in water and therefore the toxicity results can be read across. Mg2+, Cl- and CO32 - ions are all ubiquitous in the aquatic environment and are not considered to pose a risk of ecotoxicity.
Magnesium is present in all natural waters and is a major contributor to water hardness. Water from areas rich in magnesium-containing rocks may contain magnesium in the concentration range 10 to 50 mg/L. The sulfates and chlorides of magnesium are very soluble, and water in contact with such deposits may contain several hundred milligrams of magnesium per litre. This natural abundance of magnesium ions in the environment means that aquatic organisms including algae are constantly exposed to magnesium without suffering from any adverse or detrimental effects. This lack of toxicity is supported by the presented study, summarised below. Any further testing is scientifically unjustified.
A GLP guideline study was performed which assessed the acute toxicity of magnesium chloride hexahydrate (Eurofins-GAB GmbH, 2010) to algae in a limit test. The 72 h EC50 for magnesium chloride hexahydrate was found to be >100 mg/L and the NOEC was 100 mg/L, the highest concentration tested. No toxic effects were noted. The concentrations of magnesium were measured in each test solution. The EC50 based on the mean measured concentrations of magnesium is therefore equal to >18.5 mg/L and the NOEC is 18.5 mg/L. Based on these values the NOEC and EC50 for magnesium carbonate can be estimated to be 65 mg/L and >65 mg/L, respectively.
The lack of toxicity seen in this study therefore suggests that magnesium carbonate would not be acutely toxic up to the limit of its solubility in water (110 mg/L at 20 °C).
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